Tumour Viruses

Dublin Core

Title

Tumour Viruses

Subject

Tumour

Description

The first human tumor virus was discovered in the middle of the last century by Anthony Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt’s lymphoma. To date, seven viruses -EBV, KSHV, high-risk HPV, MCPV, HBV, HCV and HTLV1- have been consistently linked to different types of human cancer, and infections are estimated to account for up to 20% of all cancer cases worldwide. Viral oncogenic mechanisms generally include: generation of genomic instability, increase in the rate of cell proliferation, resistance to apoptosis, alterations in DNA repair mechanisms and cell polarity changes, which often coexist with evasion mechanisms of the antiviral immune response. Viral agents also indirectly contribute to the development of cancer mainly through immunosuppression or chronic inflammation, but also through chronic antigenic stimulation

Creator

Joanna Parish

Source

https://www.mdpi.com/books/pdfview/book/168

Publisher

MDPI - Multidisciplinary Digital Publishing Institute

Date

2016

Contributor

Baihaqi

Rights

Creative Commons

Format

Ebooks

Language

English

Type

Textbooks

Files

Citation

Joanna Parish , “Tumour Viruses,” Open Educational Resource (OER) - USK Library, accessed June 14, 2024, http://uilis.usk.ac.id/oer/items/show/2979.

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